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化化學(xué)新蟲 (小有名氣)
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[交流]
佐治亞州立大學(xué)于炳辰課題組招聘有機(jī)化學(xué)和藥物化學(xué)方向博后 已有3人參與
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導(dǎo)師簡(jiǎn)介 Dr. Bingchen Yu于2014年畢業(yè)于山東大學(xué)藥學(xué)院，獲得藥學(xué)學(xué)士學(xué)位；2018年在佐治亞州立大學(xué)化學(xué)系獲得有機(jī)化學(xué)與藥物化學(xué)博士學(xué)位。自2019年起，他先后在佐治亞州立大學(xué)和加州大學(xué)舊金山分校從事博士后研究。2023年，他加入佐治亞州立大學(xué)化學(xué)系，擔(dān)任助理教授。Dr. Yu 實(shí)驗(yàn)室有現(xiàn)有兩個(gè)NIH funding，科研資金充足。 迄今為止，Dr. Yu在包括Nature Chemistry, Chem, JACS， Angewandte Chemie和Chemical Science 在內(nèi)的高影響因子學(xué)術(shù)期刊上，以第一作者或共同作者身份發(fā)表了40篇論文，其研究成果被引用近2000次，展現(xiàn)了他在有藥物化學(xué)，化學(xué)生物學(xué)和蛋白藥物領(lǐng)域的卓越貢獻(xiàn)。 于老師對(duì)實(shí)驗(yàn)室成員給予精準(zhǔn)指導(dǎo)。 無(wú)論是實(shí)驗(yàn)遇到瓶頸時(shí)的鼓勵(lì)，還是未來(lái)職業(yè)發(fā)展的建議，他總是傾盡全力地支持。更難得的是，他愿意花時(shí)間傾聽實(shí)驗(yàn)室成員的想法，尊重每個(gè)人的獨(dú)立性，讓實(shí)驗(yàn)室充滿了自由探索的氛圍。 課題組網(wǎng)站：https://www.bingchenyu-lab.org/ https://cas.gsu.edu/profile/bingchen-yu/ Dr. Bingchen Yu graduated from the School of Pharmacy, Shandong University in 2014 with a Bachelor’s degree in Pharmacy, and obtained his Ph.D. in Organic and Medicinal Chemistry from the Department of Chemistry at Georgia State University (GSU) in 2018. Since 2019, he has conducted postdoctoral research at both Georgia State University and the University of California, San Francisco (UCSF). In 2023, he joined the Department of Chemistry at Georgia State University as an Assistant Professor. Dr. Yu’s laboratory currently holds two NIH grants, ensuring strong research funding support. To date, Dr. Yu has published 40 peer-reviewed papers as first or co-author in high-impact journals such as Nature Chemistry, Chem, Journal of the American Chemical Society (JACS), Angewandte Chemie, and Chemical Science. His work has been cited nearly 2,000 times, demonstrating his outstanding contributions to medicinal chemistry, chemical biology, and protein therapeutics. Dr. Yu is not only an exceptional scholar but also an inspiring mentor. He provides precise and thoughtful guidance to his lab members—offering encouragement when experiments face challenges and valuable advice for career development. Remarkably, he devotes time to listening to his team’s ideas and respects everyone’s independence, fostering a lab atmosphere full of curiosity and freedom for exploration. 研究方向 1. 利用擴(kuò)展密碼子技術(shù)結(jié)合鄰近觸發(fā)反應(yīng)機(jī)制，實(shí)現(xiàn)蛋白的共價(jià)交聯(lián)，用于深入研究蛋白-蛋白、蛋白-糖以及蛋白-RNA相互作用機(jī)制。 2. 通過(guò)設(shè)計(jì)并優(yōu)化小分子探針，探索和解析蛋白-蛋白相互作用的結(jié)構(gòu)與功能關(guān)系。 3. 藥物化學(xué)。抗病毒藥物以及離子通道激活劑開發(fā)。 4. 新型高通量藥物篩選平臺(tái)的設(shè)計(jì)和開發(fā)。 實(shí)驗(yàn)室研究課題高度學(xué)科交叉，涉及有機(jī)化學(xué)，分子生物學(xué)和計(jì)算機(jī)等多種學(xué)科。 1. Developing covalent protein crosslinking strategies by combining genetic code expansion and proximity-enabled reaction mechanisms. 2. Designing and optimizing small-molecule probes to elucidate structure–function relationships in protein–protein interactions. 3. Medicinal chemistry: development of antiviral drugs and ion channel activators. 4. Design and development of novel high-throughput drug screening platforms. Dr. Yu’s research is highly interdisciplinary, integrating organic chemistry, molecular biology, and computational sciences. 博士生招聘信息 1. 招聘方向：有機(jī)化學(xué)，藥物化學(xué)和化學(xué)生物學(xué) 2. 招聘條件： • 在有機(jī)化學(xué)，藥物化學(xué)和化學(xué)生物學(xué)方向獲得博士學(xué)位或者即將獲得博士學(xué)位 • 發(fā)表過(guò)高水平的一作文章 • 同時(shí)具有有機(jī)化學(xué)和生物學(xué)背景的優(yōu)先考慮 • 熱愛(ài)科研，具有強(qiáng)烈的創(chuàng)新意識(shí)和團(tuán)隊(duì)合作精神。 3. 福利待遇： • $ 60,000 per year + benefit； • 提供一流的研究設(shè)備和資源，支持參加國(guó)際會(huì)議與合作交流。 4. 工作地點(diǎn)： 美國(guó)亞特蘭大，佐治亞州立大學(xué)化學(xué)系，享有良好的學(xué)術(shù)氛圍及合作環(huán)境。 5. 申請(qǐng)材料 （提交英文材料）： • CV； • Personal statement including research interest and research plan 6. 申請(qǐng)方式：請(qǐng)將以上材料發(fā)送至以下郵箱：byu8@gsu.edu，郵件主題請(qǐng)注明“post-doc application + name”。 7. 工作時(shí)間：2026 年春季 1. Research Areas: Organic Chemistry, Medicinal Chemistry, and Chemical Biology 2. Requirements: • Ph.D. in Organic Chemistry, Medicinal Chemistry, or Chemical Biology (completed or soon to be completed) • Strong first-author publications • Candidates with both chemistry and biology backgrounds are preferred • Passion for research, creativity, and strong teamwork spirit 3. Compensation and Benefits: • $60,000 per year + benefits • Access to world-class research facilities and funding for international conferences and collaborations 4. Workplace: Department of Chemistry, Georgia State University, Atlanta, USA, a highly collaborative and dynamic academic environment. 5. Application Materials (in English): • Curriculum Vitae (CV) • Personal statement including research interests and future research plan 6. Application Method: Email materials to byu8@gsu.edu, with the subject line: “post-doc application + [Your Name]”. 7. Start Date: Spring 2026 實(shí)驗(yàn)室環(huán)境 本課題組擁有化學(xué)合成實(shí)驗(yàn)室和細(xì)胞培養(yǎng)實(shí)驗(yàn)室，配備完善的實(shí)驗(yàn)儀器和設(shè)施，可支持有機(jī)合成、分子生物學(xué)、蛋白表達(dá)與純化、細(xì)菌培養(yǎng)以及哺乳動(dòng)物細(xì)胞培養(yǎng)等多領(lǐng)域研究工作。課題組擁有自己的LC-MS/HPLC、多臺(tái)自動(dòng)過(guò)柱機(jī)、PCR儀、Nanodrop、成像系統(tǒng)（imaging system）以及生物安全柜（safety cabinet）。 此外，佐治亞州立大學(xué)化學(xué)系設(shè)有多個(gè)科研中心，例如診斷與治療中心（The Center for Diagnostics and Therapeutics）和疾病分子基礎(chǔ)研究項(xiàng)目（Molecular Basis of Disease Program），并配備一流的公共實(shí)驗(yàn)平臺(tái)（core facilities）。這些平臺(tái)包括： • 核磁共振儀（NMR）： 400 MHz和600 MHz； • 質(zhì)譜儀： MALDI-TOF和Orbitrap-MS/MS； • 流式細(xì)胞儀（flow cytometry）； • 共聚焦顯微鏡（confocal microscopy）； • 多通道多肽合成儀（multi-channel peptide synthesizer）。 完善的實(shí)驗(yàn)條件和強(qiáng)大的科研支持平臺(tái)，為課題組的創(chuàng)新研究提供了堅(jiān)實(shí)保障。 佐治亞州立大學(xué)簡(jiǎn)介 佐治亞州立大學(xué)（Georgia State University，簡(jiǎn)稱GSU）是美國(guó)一級(jí)公立大學(xué)，成立于1913年，位于美國(guó)佐治亞州亞特蘭大市。亞特蘭大是全美前十大城市之一，氣候宜人，交通便利，生活設(shè)施完善。市區(qū)內(nèi)擁有眾多中餐廳和亞洲超市，為國(guó)際學(xué)生提供了豐富的飲食選擇。此外，亞特蘭大擁有北美最大的水族館、可口可樂(lè)博物館，以及美國(guó)有線電視新聞網(wǎng)（CNN）和達(dá)美航空總部。這座城市也是微軟、谷歌、奔馳等全球知名企業(yè)的重要分支和研究中心所在地，吸引了大量的科技創(chuàng)新和商業(yè)機(jī)會(huì)，使得亞特蘭大成為一個(gè)充滿活力和國(guó)際化的都市環(huán)境。佐治亞州立大學(xué)作為其中的重要一員，憑借其強(qiáng)大的學(xué)術(shù)實(shí)力和多樣化的資源，為學(xué)生提供了卓越的教育體驗(yàn)和無(wú)限的成長(zhǎng)空間。 The Yu Lab houses both chemical synthesis and cell culture laboratories, equipped for various research areas such as organic synthesis, molecular biology, protein expression and purification, bacterial culture, and mammalian cell studies. Facilities in the Yu lab include LC-MS/HPLC, multiple automated chromatography systems, PCR machines, Nanodrop, imaging systems, and biosafety cabinets. GSU’s Department of Chemistry also hosts multiple research centers—such as the Center for Diagnostics and Therapeutics (CDT) and the Molecular Basis of Disease (MBD) Program—as well as shared core facilities, including: • NMR spectrometers (400 MHz and 600 MHz) • Mass spectrometers (MALDI-TOF and Orbitrap-MS/MS) • Flow cytometry • Confocal microscopy • Multi-channel peptide synthesizer About Georgia State University Georgia State University (GSU) is a leading public research university in the United States, founded in 1913 and located in Atlanta, Georgia—one of the top ten metropolitan cities in the U.S. Atlanta offers a pleasant climate, excellent infrastructure, and convenient transportation. The city has a vibrant Asian community, with numerous Chinese restaurants and supermarkets, offering international students a comfortable living environment. Atlanta is home to major attractions such as the Georgia Aquarium (the largest in North America), World of Coca-Cola, CNN Headquarters, and Delta Airlines Headquarters. It also hosts regional offices and research centers for global companies including Microsoft, Google, and Mercedes-Benz, making it a hub for innovation and opportunity. As a major academic institution in this thriving city, Georgia State University provides students and researchers with an outstanding academic environment, abundant resources, and unlimited opportunities for professional growth. |
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