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hbao2019新蟲 (初入文壇)
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University of Virginia 招全獎博士研究生, 博士后和訪問學(xué)者/學(xué)生 已有1人參與
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招聘信息： 弗吉尼亞大學(xué)生物物理和生理系 (University of Virginia, Molecular Physiology and Biological Physics) Dr. Huan Bao 課題組誠招全獎博士研究生, 博士后和訪問學(xué)者/學(xué)生 招聘方向和課題組簡介: protein engineering/structural biology/nanomedicine The Bao research group focuses on the membrane biology of cell communication (Bao et al., 2016, NSMB; Bao et al., 2018, Nature; Zhang et al. 2021, Nat Commun; Courtney et al., 2022 NSMB; Xiong et al., 2022 Cell; Shin et al., 2024 Nano Let; Ren et al., 2025 Nat Commun). Using a combination of biochemical reconstitution, cell biology and structural approaches, we seek to elucidate how membranes and membrane proteins regulate life and death. Based on the findings from our basic research, we are also interested in reprogramming membrane biology for therapeutic development against human disease. We strive to create a supportive environment that inspires learning, innovation, and passion for scientific discovery. People in the lab will have numerous opportunities to explore their own research interest. We emphasize rigorous training and open communication, and work as a team to tackle fundamental challenges in membrane biology. The lab is located in the Membrane Biology Center at the University of Virginia, with ample access to well-equipped imaging, flow cytometry and cryogenic electron microscopy cores in the same building. In addition, we are extensively collaborating with experts at UVA and across US to explore research and therapeutic applications of membrane biology. The lab is currently well-funded by multiple federal and private grants from NIH, AFAR, and CHRB. We are looking for 2-3 highly motivated postdocs/students in the following areas: 1) Structural membrane biology using cryoEM/ET; 2) Molecular mechanisms of membrane damage and repair; 3) Computational protein and peptide design; 4) Programming protein degradation and cell death; 5) Immune engineering with mRNA lipid nanoparticles against infections and cardiovascular diseases. Dr. Bao obtained his B.S. in Biological Science from Wuhan University and his Ph.D. in Biochemistry and Molecular Biology from the University of British Columbia. As a Human Frontier Science Program postdoctoral fellow, he investigated the molecular mechanism of synaptic transmission at the University of Wisconsin-Madison and Howard Hughes Medical Institute. Dr. Bao has made fundamental contribution to our understanding of membrane transport, receptor signaling and exocytosis. His work has been recognized by the Chinese Government Award for Outstanding Students Abroad, HFSP Career Development Award and NIH Director’s New Innovator Award. Applicants should send a cover letter and CV to Dr. Huan Bao via email (baoh@virginia.edu). Students interested in the lab need to apply through the BIMS PhD program. Exceptional candidates can join the lab through direct match. GREs are not required (optional). Lab website: https://sites.google.com/view/baolab/ 招聘要求和待遇 Previous experiences in biochemistry, structural biology, protein design, animal models, nanomedicine or cell biology are preferred. Salary for postdoc is commensurate with experience and expertise, ranging from 60K to 80K per year plus insurance and benefits. 大學(xué)簡介 The University of Virginia (ranked at #24 by U.S. News) is founded by the third president of US, Thomas Jefferson, in 1819 at Charlottesville, a beautiful college town close to Washington-DC and Virginia Beach, and one of the ten best places to live in US. 實驗室專注于細(xì)胞通訊和交流的膜生物學(xué) (Bao et al.，2016，NSMB；Bao et al., 2018，Nature；Zhang et al., 2021, Nat Commun；Xiong et al., 2022, Cell; Shin et al., 2024 Nano Let; Ren et al., 2025 Nat Commun). 通過生化重組、細(xì)胞生物學(xué)和結(jié)構(gòu)生物學(xué)等方法，我們致力于闡明膜蛋白如何介導(dǎo)分泌和細(xì)胞死亡�；谖覀儗τ谶@些基礎(chǔ)研究的發(fā)現(xiàn)，我們將重新編程膜生物學(xué)以開發(fā)針對人類疾病的治療方法。我們努力創(chuàng)造一個激發(fā)學(xué)習(xí)、創(chuàng)新和對科學(xué)發(fā)現(xiàn)的熱情的研究培養(yǎng)環(huán)境。實驗室的成員將有許多機會探索他們自己的研究興趣。我們強調(diào)嚴(yán)格的培訓(xùn)和開放的溝通，團隊協(xié)作以應(yīng)對膜生物學(xué)中的研究挑戰(zhàn)。實驗室位于弗吉尼亞大學(xué)的膜生物學(xué)中心，該中心配備了設(shè)備齊全的成像、流式細(xì)胞儀和冷凍電子顯微鏡設(shè)施。得益于多項 NIH 和 UVA 的資助，我們已經(jīng)同多個課題組展開了前沿科學(xué)問題的探索研究，期待對以下領(lǐng)域感興趣的博士生和博士后加入實驗室的研究工作： 1） 結(jié)構(gòu)膜生物學(xué)和冷凍電鏡； 2） 膜損傷和修復(fù)的分子機制； 3） 計算機輔助蛋白和多肽設(shè)計； 4） 蛋白質(zhì)降解和死亡； 5） 納米免疫工程和核酸藥物開發(fā)。 有生物化學(xué)，結(jié)構(gòu)生物學(xué)，機器學(xué)習(xí)，蛋白質(zhì)設(shè)計，納米醫(yī)學(xué)或細(xì)胞生物學(xué)方面的相關(guān)經(jīng)驗者優(yōu)先考慮。博士后薪水與經(jīng)驗和專業(yè)知識相稱，年薪范圍為 60,000 到 80,000 美元，另有保險和福利。弗吉尼亞大學(xué)由美國第三任總統(tǒng)托馬斯·杰斐遜于 1819 年在夏洛茨維爾市創(chuàng)辦，這是一座美麗的大學(xué)城，靠近華盛頓特區(qū)和弗吉尼亞海灘，也是美國十大最佳居住地之一。 申請人應(yīng)通過電子郵件將求職信和簡歷發(fā)送至：baoh@virginia.edu. 實驗室網(wǎng)站：https://sites.google.com/view/baolab/ |
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hbao2019
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