 |
 |
 |
 |
 |
 |
||
 |
 |
 |
 |
 |
| 3 | 1/1 | 返回列表 |
| 查看: 1175 | 回復(fù): 2 | |||
kusu新蟲 (初入文壇)
|
[交流]
香港大學(xué)李嘉誠醫(yī)學(xué)院招全職博后-生物醫(yī)學(xué)/干細胞/機械傳感/再生醫(yī)學(xué)/單細胞
|
|
香港大學(xué)李嘉誠醫(yī)學(xué)院 生物醫(yī)學(xué)學(xué)院 謝賞恩教授 招聘1-2名全職博后 Kathryn Cheah教授為香港科學(xué)院成員、世界科學(xué)院院士，是一位發(fā)育遺傳學(xué)家。于英國劍橋大學(xué)獲得分子生物學(xué)博士學(xué)位，曾在英國曼徹斯特大學(xué)和帝國癌癥研究基金會從事博士后研究。 在香港大學(xué)，她曾擔(dān)任生物化學(xué)系主任和生殖、發(fā)育與生長中心主任。 由于對基質(zhì)生物學(xué)的貢獻，她被授予英國基質(zhì)生物學(xué)學(xué)會獎?wù)轮v座 2022。 隨著全球人口老齡化，基因組和再生醫(yī)學(xué)將在幫助保持健康成長和生活質(zhì)量方面發(fā)揮關(guān)鍵作用。她使用人類和小鼠胚胎干細胞和轉(zhuǎn)基因小鼠作為模型來研究發(fā)育和疾病，并開發(fā)治療軟骨疾�。ɡ绻顷P(guān)節(jié)炎）和低骨量（例如骨質(zhì)疏松癥）和椎間盤退變的方法。在國際上，她是eLife 的高級編輯，還擔(dān)任骨科研究雜志編輯委員會的編輯顧問。 更多具體介紹請參見PI主頁：https://www.sbms.hku.hk/staff/kathryn-song-eng-cheah Post-doctoral Fellow on Mechanotransduction in Stem Cell Biology in the School of Biomedical Sciences, HKU Applications are invited for appointment as a Postdoctoral Fellow in the School of Biomedical Sciences, to commence as soon as possible for one or two years, with the possibility of renewal. Applicants should have a Ph.D. degree, preferably in Biology, Biomedical Sciences, Medical Engineering, or a related discipline. Experience in cell and molecular biology would be preferred. Applicants should also be organized, self-motivated, committed to the project schedule, and able to work independently and in a team. The appointee will participate in a multidisciplinary RGC-funded Collaborative Research Fund (CRF) project (see below) relating to the influence of the extracellular matrix on lineage-directed differentiation of human embryonic stem cells to intervertebral disc stem cells. For further information, please get in touch with Professor Kathryn Cheah (kathycheah@hku.hk) or Dr. Cheng-Han Yu (chyu1@hku.hk). The appointee will gain experience in stem cell biology, functional genomics, and single-cell biology. A highly competitive salary commensurate with qualifications and experience will be offered, in addition to annual leave and medical benefits. Project: Analyses of progenitors and differentiation trajectories in the nucleus pulposus and their relevance in intervertebral disc degeneration Intervertebral disc disease (IDD) and associated low back pain is an aging disorder of significant clinical burden. A likely disease-causing mechanism of IDD is the impairment of the reparative capacity of the intervertebral disc (IVD) tissues in the spine. The nucleus pulposus (NP) forms the central hydrated gelatinous core of the IVD. In IDD, the NP\'s mechanical strength and shock-absorbing capacity in the disc declines. But there is limited knowledge of the influence of the extracellular environment on the molecular characteristics and function of these cells in maintaining a healthy disc. In this project, we aim to study the role of extracellular matrix stiffness and mechanotransduction in NP cell differentiation and fate. Mechanical loading of the IVD is a crucial factor inducing cellular stress, matrix stiffening, and fibrosis that contribute to disc degeneration. Stiffened microenvironment can promote cell differentiation, proliferation, and expression of adhesion and ECM proteins. We will determine the impact of altering matrix stiffness after culturing in the stiffness-defined functionalized matrices on the differentiation of human embryonic stem cells to NP cells and their transcriptome and gene regulatory network. The insights will be linked and applied to the ongoing meta-analyses of genomic data on IDD. |
回復(fù)此樓» 猜你喜歡
324求調(diào)劑
已經(jīng)有6人回復(fù)
-
A區(qū)一本交叉課題組，低分調(diào)劑，招收機械電子信息通信等交叉方向
已經(jīng)有28人回復(fù)
-
334求調(diào)劑
已經(jīng)有7人回復(fù)
-
085602高分子方向求調(diào)劑
已經(jīng)有4人回復(fù)
-
083000，總分284，求調(diào)劑
已經(jīng)有3人回復(fù)
-
不限學(xué)校專業(yè)的調(diào)劑同學(xué)看過來
已經(jīng)有7人回復(fù)
-
303求調(diào)劑
已經(jīng)有5人回復(fù)
-
復(fù)試調(diào)劑
已經(jīng)有7人回復(fù)
-
新疆大學(xué)地質(zhì)與礦業(yè)工程學(xué)院招生
已經(jīng)有6人回復(fù)
-
2026年博士名額撿漏
已經(jīng)有4人回復(fù)
» 本主題相關(guān)商家推薦: (我也要在這里推廣)
kusu
新蟲 (初入文壇)
- 應(yīng)助: 0 (幼兒園)
- 金幣: 22.5
- 帖子: 4
- 在線: 1.7小時
- 蟲號: 2565960
- 注冊: 2013-07-26
- 專業(yè): 細胞增殖、生長與分化
2樓2023-04-25 14:16:03
kusu
新蟲 (初入文壇)
- 應(yīng)助: 0 (幼兒園)
- 金幣: 22.5
- 帖子: 4
- 在線: 1.7小時
- 蟲號: 2565960
- 注冊: 2013-07-26
- 專業(yè): 細胞增殖、生長與分化
3樓2023-04-26 16:34:29
相關(guān)版塊跳轉(zhuǎn)
我要訂閱樓主 kusu 的主題更新
| 3 | 1/1 | 返回列表 |
| 最具人氣熱帖推薦 [查看全部] | 作者 | 回/看 | 最后發(fā)表 | |
|---|---|---|---|---|
|
[考研] 324求調(diào)劑 +4 | wxz2 2026-03-03 | 6/300 |
|
|---|---|---|---|---|
|
[考研] 083000，總分284，求調(diào)劑 +3 | 徐yr 2026-03-04 | 3/150 |
|
|
|
[考研] 新疆大學(xué)地質(zhì)與礦業(yè)工程學(xué)院招生 +4 | another12 2026-03-04 | 6/300 |
|
|
|
[考研] 085600材料與化工 298 調(diào)劑 +9 | 小西笑嘻嘻 2026-03-03 | 9/450 |
|
|
|
[考研] 322分 085600求調(diào)劑，有互聯(lián)網(wǎng)+國金及主持省級大創(chuàng)經(jīng)歷 +6 | 熊境喆 2026-03-04 | 6/300 |
|
|
|
[考研] 0703化學(xué)求調(diào)劑，總分320分，一志愿中南民族大學(xué) +3 | 19286712440 2026-03-04 | 3/150 |
|
|
|
[考研] 0703化學(xué) 一志愿東北大學(xué) 279分求調(diào)劑 +4 | 聶樂平 2026-03-03 | 4/200 |
|
|
|
[考研] 281求調(diào)劑 +3 | 我是小小蔥蔥 2026-03-03 | 5/250 |
|
|
|
[考博] 26申博 求博導(dǎo) +3 | 愛讀書的小帥 2026-02-28 | 5/250 |
|
|
|
[考研] 主題 +3 | realstar2006 2026-02-27 | 3/150 |
|
|
|
[考研] 化工專碩調(diào)劑 +4 | 利好利好. 2026-03-03 | 7/350 |
|
|
|
[考研] 江蘇省農(nóng)科院招調(diào)劑1名 +5 | Qwertyuop 2026-03-01 | 5/250 |
|
|
|
[考研] 化工335求調(diào)劑 +5 | 摸摸貓貓頭 2026-03-02 | 5/250 |
|
|
|
[考研] 化工京區(qū)271求調(diào)劑 +7 | 11ing 2026-03-02 | 7/350 |
|
|
|
[考研]
 高分子化學(xué)與物理調(diào)劑
+6
|
好好好1233 2026-02-28 | 16/800 |
|
|
|
[考研] 321求調(diào)劑一志愿東北林業(yè)大學(xué)材料與化工英二數(shù)二 +5 | 蟲蟲蟲蟲蟲7 2026-03-01 | 9/450 |
|
|
|
[考研] 284求調(diào)劑 +10 | 天下熯 2026-02-28 | 11/550 |
|
|
|
[考研] 材料調(diào)劑 +6 | 愛擦汗的可樂冰 2026-02-28 | 7/350 |
|
|
|
[考研] 322求調(diào)劑 +3 | 熊境喆 2026-03-01 | 3/150 |
|
|
|
[考研] 295復(fù)試調(diào)劑 +3 | 簡木ChuFront 2026-03-01 | 3/150 |
|