博士后?

具體工作地點(diǎn):

法國普瓦捷環(huán)境與材料研究所

薪金:

待議

項(xiàng)目簡(jiǎn)介：用于設(shè)計(jì)可再生表面活性劑的低聚糖合成。
博士后職位簡(jiǎn)介：這個(gè)為期一年的博士后職位由 IC2MP 和 SYENSQO 合作提供，旨在開發(fā)一種催化
反應(yīng)，從天然多糖中生產(chǎn)生物基表面活性劑，用于家庭個(gè)人護(hù)理中的各種應(yīng)用。在先前工作的基
礎(chǔ)上，IC2MP 的策略將包括多糖的催化控制解聚，以獲得具有所需分子量的寡糖及其進(jìn)一步的功
能化。將優(yōu)先使用工業(yè)催化劑。催化反應(yīng)將在高壓釜中進(jìn)行，并通過尺寸排阻色譜、NMR 和質(zhì)譜
法進(jìn)行監(jiān)測(cè)。在這種情況下，該項(xiàng)目將受益于對(duì) IC2MP 的 PLATINA 分析平臺(tái)的訪問。低聚糖的物
理化學(xué)性質(zhì)及其生物降解性將由 SYENSQO 評(píng)估。
工作內(nèi)容簡(jiǎn)介：該研究將從文獻(xiàn)綜述開始，以（1）評(píng)估此類反應(yīng)最有效的工業(yè)催化劑，以及
（2）確定與該研究相關(guān)的科學(xué)和技術(shù)挑戰(zhàn)。然后，候選人將負(fù)責(zé)進(jìn)行第一次催化測(cè)試。在初始
階段，候選人將使用均相酸催化劑。此階段旨在優(yōu)化所有反應(yīng)參數(shù)，如壓力、溫度、濃度、氣氛
等。在第二階段，候選人將專注于使用非均相催化劑。在這些研究任務(wù)中，將特別考慮反應(yīng)選擇
性、催化劑消耗、能耗和反應(yīng)器生產(chǎn)率等性能標(biāo)準(zhǔn)，以指導(dǎo)研究。
IC2MP 和 SYENSQO 之間將定期舉行遠(yuǎn)程或面對(duì)面的工作會(huì)議，以確保研究項(xiàng)目的順利進(jìn)行，并在
必要時(shí)調(diào)整初始目標(biāo)。在研究結(jié)束時(shí)，候選人將制作一份報(bào)告提交給 SYENSQO。
期望技能：擁有化學(xué)博士學(xué)位，候選人應(yīng)具有應(yīng)用于精細(xì)/有機(jī)化學(xué)的催化專業(yè)知識(shí)，并對(duì)分析
（SEC、HPLC、NMR、質(zhì)譜）有濃厚的興趣。有多糖或糖化學(xué)經(jīng)驗(yàn)者優(yōu)先。候選人還應(yīng)該充滿好奇
心、保持嚴(yán)謹(jǐn)?shù)膽B(tài)度，并能夠作為國際團(tuán)隊(duì)的一員工作。
關(guān)于我們：普瓦捷環(huán)境與材料研究所（IC2MP）是法國國家科學(xué)研究中心（CNRS）和普瓦捷大學(xué)
（University of Poitiers）的聯(lián)合研究單位，專注于可持續(xù)反應(yīng)/產(chǎn)物的設(shè)計(jì) （https://ic2mp.labo.univ-
poitiers.fr ）。它是一個(gè)跨學(xué)科研究所，致力于（1）生態(tài)高效技術(shù)（催化、生物溶劑、可再生能
源、替代技術(shù)等）的開發(fā)，以及（2）生態(tài)系統(tǒng)中有機(jī)分子的轉(zhuǎn)移和生物積累。IC2MP 有能力通
過提供從設(shè)計(jì)到環(huán)境影響的科學(xué)和技術(shù)解決方案，在全球范圍內(nèi)整合化合物轉(zhuǎn)化過程的關(guān)鍵步驟
。 Syensqo 是一家科技公司，致力于開發(fā)突破性的解決方案，以改善我們的生活、工作、旅行和
娛樂方式。受 Ernest Solvay 于 1911 年發(fā)起的科學(xué)委員會(huì)的啟發(fā)，我們匯集了偉大的思想，擁有
一支由 13,000 多名員工組成的多元化全球團(tuán)隊(duì)（https://www.syensqo.com/en/），不斷突破科學(xué)和
創(chuàng)新的極限，造福我們的客戶。我們的解決方案有助于為家庭、食品和消費(fèi)品、飛機(jī)、汽車、電
池、智能設(shè)備和醫(yī)療保健應(yīng)用中提供更安全、更清潔、更可持續(xù)的產(chǎn)品。我們的創(chuàng)新能力使我們
能夠?qū)崿F(xiàn)循環(huán)經(jīng)濟(jì)的雄心壯志，并探索推動(dòng)人類進(jìn)步的突破性技術(shù)。聯(lián)系人：
francois.jerome@univ-poitiers.fr （IC2MP） et； antoine.beuque@syensqo.com （SYENSQO）

Synthesis of oligosaccharides for the design of renewable surfactants

We are looking for: a one-year postdoc, in collaboration between IC2MP and SYENSQO, which aims to
develop a catalytic reaction to produce bio-based surfactants from natural polysaccharides for various
applications in Home Personal Care.
We count on you for: Building on previous works, the strategy at IC2MP will consist of a catalytic
controlled depolymerization of polysaccharides to obtain oligosaccharides with desired molecular
weights and their further functionalization. Industrial catalysts will be preferentially used. The catalytic
reactions will be carried out in autoclaves and monitored by size-exclusion chromatography, NMR, and
mass spectrometry. In this context, the project will benefit from access to the PLATINA analysis platform
belonging to IC2MP. The physicochemical properties of the oligosaccharides, as well as their
biodegradability, will be evaluated by SYENSQO.
The research will begin with a literature review to (1) assess the most effective industrial catalysts for
this type of reaction and (2) identify the scientific and technological challenges associated with this
research. The candidate will then be in charge of performing the first catalytic tests. Initially,
homogeneous acid catalysts will be used. This phase aims to optimize all reaction parameters such as
pressure, temperature, concentration, atmosphere, etc. In the second phase, the candidate will focus on
using heterogeneous catalysts. Throughout these research tasks, performance criteria such as reaction
selectivity, catalyst consumption, energy consumption, and reactor productivity will be particularly
considered to guide the research.Regular working meetings between IC2MP and SYENSQO, either
remotely or in person, will take place to ensure the smooth progress of the research project and, if
necessary, adjust the initial objectives. At the end of the study, the candidate will produce a report to be
submitted to SYENSQO.
Expected skills: Holder of PhD in chemistry, the candidate should have expertise in catalysis applied to
fine/organic chemistry and a strong interest in analysis (SEC, HPLC, NMR, mass spectrometry). Prior
experience in polysaccharide or sugar chemistry would be an advantage. The candidate should also be
curious, rigorous, and able to work as part of an international team.
About us: The Institut de Chimie des Milieux et Matériaux de Poitiers (IC2MP) is a joint research unit
between CNRS and the University of Poitiers, focusing on the design of sustainable reactions/products
(https://ic2mp.labo.univ-poitiers.fr ). It is an interdisciplinary institute working (1) on the development
of eco-efficient technologies (catalysis, bio-solvents, renewable energies, alternative technologies, etc.)
and (2) on the transfer and bioaccumulation of organic molecules in ecosystems. IC2MP has the capacity
to globally integrate the key steps of a chemical compound transformation process by providing
scientific and technological solutions, from design to environmental implications.
Syensqo is a science company developing groundbreaking solutions that enhance the way we live, work,
travel, and play. Inspired by the scientific councils that Ernest Solvay initiated in 1911, we bring great
minds together to push the limits of science and innovation for the benefit of our customers, with a
diverse, global team of more than 13,000 associates (https://www.syensqo.com/en/). Our solutions
contribute to safer, cleaner, and more sustainable products found in homes, food and consumer goods,
planes, cars, batteries, smart devices, and healthcare applications. Our innovation power enables us to
deliver on the ambition of a circular economy and explore breakthrough technologies that advance

humanity.Contact : francois.jerome@univ-poitiers.fr （IC2MP）et； antoine.beuque@syensqo.com
(SYENSQO)

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