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新加坡國立大學生物藥物化學 DENG Lih We 博士后
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DENG Lih Wen email: bchdlw@nus.edu.sg 新加坡國立大學藥學院招聘 chemical biology/drug discovery Research Fellow PI Name DENG Lih Wen email: bchdlw@nus.edu.sg Department Biochemistry Position Research Fellow Salary Range SGD 5,000 – SGD 6,000 The National University of Singapore invites applications for Research Fellow to conduct a research project on Development and Application of innovative bioactivity assays for drug discovery for cancer therapy” in the Department of Biochemistry and Centre for Cancer Research, NUS. The research fellow will work in close collaboration with a multidisciplinary team including chemists, pharmaceutical scientists, bioengineers, and cancer research scientists. The role is lab-based and encompasses in vitro and in vivo assay designs, bioactivity validation and development of mechanistic assays for hit validation and lead compound generation. Appointments will be made on a one-year contract basis from 1 July 2022 for the possibility of extension for 3 years. Qualifications 1) Have a PhD degree in. in biochemistry, pharmaceutical science, biomedical science, pharmacology or a related discipline. 2) At least 6 years of research experience with good publication track record in the related area and is able to work independently and in a team. 3) A basic understanding of molecular biology techniques and expression/purification of proteins in bacteria and/or mammalian cells as well as practical experience in mammalian cell culture and immunofluorescent microscopy is essential. 4) Familiar with high-throughput cell culture-based anticancer drug screening in both 2D and 3D in vitro tumor models. Experience in implementation of anticancer drug delivery for in vivo cancer treatment using xenograft mouse model is preferable. 5) Great skills in developing robust assays in support of medicinal chemistry or biological programs including both in vitro biochemical (e.g. enzymes) and cellular (e.g. reporter assay) development and various assay technologies and read-outs suitable for support of drug development. Main duties and responsibilities The Research Fellow will be able to: • Manage the planning and executions of the research projects in a research team; • Train and supervise research staff/postgraduate students recruited to the research project; • Draft manuscripts for publication and proposals for research grants; • Analyze and interpret obtained data as a member of a cross-disciplinary team • Maintain the highest standard of professional conduct and record keeping in accordance with policies and procedures. Interested individuals should send an application including a cover letter (with statement of research interest and career goals), curriculum vitae and the contact information of three referees in one single PDF to Associate Professor DENG Lih Wen (bchdlw@nus.edu.sg). Remuneration will be commensurate with the candidate’s qualifications and experience. Only shortlisted candidates will be notified. |
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