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藥動(dòng)學(xué)參數(shù)的達(dá)峰時(shí)間Tmax為什么由中位數(shù)描述?
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藥動(dòng)學(xué)參數(shù)的達(dá)峰時(shí)間Tmax為什么由中位數(shù)描述? 而其它的參數(shù)如Cmax則用均值±SD描述。 求問(wèn),謝謝大家 |
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| the tmax variable is a categorical variable that can only take values based on the planned sampling scheme. Thus if your planned sample schedule includes 0, 1, 2, 4, 6, and 8 hours, you cannot have a sample at 1.5 or 10 hours (unless there was a deviation). Thus the expected values for tmax are confined to some pre-selected categories. Thus when you summarize tmax results, you should NOT use averages and standard deviations, as they do not accurately describe the distribution of values. Instead, you should use medians and ranges. The median is the “middle” of the data, and the range represents the “extremes” of the data. |
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